BDBM530441 (S*)-7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H-1,2,4-triazol-3-yl)-4-isopropyl- 2-(o-tolyl)isoquinolin-1(2H)-one.::WO2022070068, Example 13::WO2022070068, Example 22

SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1nc([C@H](C)O)n(C)n1

InChI Key InChIKey=GFJXHYALUUKZRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530441   

LigandPNGBDBM530441(WO2022070068, Example 22 | (S*)-7-Fluoro-6-(5-(1-h...)
Affinity DataIC50: 0.480nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530441(WO2022070068, Example 22 | (S*)-7-Fluoro-6-(5-(1-h...)
Affinity DataIC50: 1.10nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068