BDBM530439 (R*)-7-Fluoro-6-(2-(1-hydroxyethyl)-1-methyl-1H-imidazol-4-yl)-4-isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one.::WO2022070068, Example 11

SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1cn(C)c(n1)[C@@H](C)O

InChI Key InChIKey=YHGMLYGXHNZUJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530439   

LigandPNGBDBM530439((R*)-7-Fluoro-6-(2-(1-hydroxyethyl)-1-methyl-1H-im...)
Affinity DataIC50: 0.510nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530439((R*)-7-Fluoro-6-(2-(1-hydroxyethyl)-1-methyl-1H-im...)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human DHODH using dihydroorotate and CoQ6 as substrate by DCIP dye based spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed