BDBM530430 6-(6-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin- 1(2H)-one.::WO2022070068, Example 2

SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1ccc(C)c(N)n1

InChI Key InChIKey=SMPITILEMXABBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530430   

LigandPNGBDBM530430(6-(6-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopro...)
Affinity DataIC50: 0.180nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530430(6-(6-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopro...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human DHODH using dihydroorotate and CoQ6 as substrate by DCIP dye based spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed