BDBM529999 (3R)-4-(2,2- dimethylbutanoyl)- 3-methyl-3,5- dihydro-2H- pyrido[3,4- f][1,4]oxazepine-9- carbonitrile::US11203600, Example 75

SMILES CCC(C)(C)C(=O)N1Cc2cncc(C#N)c2OC[C@H]1C

InChI Key InChIKey=CLQBXHRSDNBDKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529999   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529999((3R)-4-(2,2- dimethylbutanoyl)- 3-methyl-3,5- dihy...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent