BDBM529991 4-[2-methyl-2- (trifluoromethyl) butanoyl]-3,5-dihydro- 2H- pyrido[3,4f][1,4] oxazepine-9- carbonitrile::US11203600, Example 67

SMILES CCC(C)(C(=O)N1CCOc2c(C1)cncc2C#N)C(F)(F)F

InChI Key InChIKey=PCUGTXMUMRXMKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529991   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529991(4-[2-methyl-2- (trifluoromethyl) butanoyl]-3,5-dih...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent