BDBM529957 3,3-difluoro-1-(7- fluoro-2,3,4,5- tetrahydro-1,4- benzoxazepin-4-yl)- 2,2- dimethylpropan-1- one::US11203600, Example 33

SMILES CC(C)(C(F)F)C(=O)N1CCOc2ccc(F)cc2C1

InChI Key InChIKey=YHTQVVTXFGGWLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529957   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529957(3,3-difluoro-1-(7- fluoro-2,3,4,5- tetrahydro-1,4-...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent