BDBM529947 4-(3,3-difluoro-2,2- dimethyl- propanoyl)-3,5- dihydro-2H-1,4- benzoxazepine-9- carbonitrile::US11203600, Example 23

SMILES CC(C)(C(F)F)C(=O)N1CCOc2c(C1)cccc2C#N

InChI Key InChIKey=DRNBKERTNGHPLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529947   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529947(4-(3,3-difluoro-2,2- dimethyl- propanoyl)-3,5- dih...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent