BDBM529945 3,3-difluoro-2,2- dimethyl-1-(3- methyl-2,3- dihydrobenzo[f] [1,4]oxazepin- 4(5H)-yl)propan- 1-one::US11203600, Example 21

SMILES CC1COc2ccccc2CN1C(=O)C(C)(C)C(F)F

InChI Key InChIKey=NLCULRLEONBCRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529945   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529945(3,3-difluoro-2,2- dimethyl-1-(3- methyl-2,3- dihyd...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent