BDBM529942 3,3-difluoro-1-(9- fluoro-3,5-dihydro- 2H-1,4- benzoxazepin-4-yl)- 2,2-dimethyl-butan- 1-one::US11203600, Example 18

SMILES CC(F)(F)C(C)(C)C(=O)N1CCOc2c(F)cccc2C1

InChI Key InChIKey=FWAPRRYLRDWHMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529942   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529942(3,3-difluoro-1-(9- fluoro-3,5-dihydro- 2H-1,4- ben...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent