BDBM529582 US11203586, Example 33

SMILES C[C@H]1CN1S(=O)(=O)NCC(=O)N(C(C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)c1cc(F)cc(c1)C#N

InChI Key InChIKey=UVFOCJLEVXNCOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529582   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM529582(US11203586, Example 33)
Affinity DataIC50: 100nMAssay Description:The specific operation was as follows: 2.5 μl of the compound diluted in a 3-fold gradient was added to a 384-well plate, followed by adding 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent