BDBM529538 2-(3-fluoro-4-methoxyphenoxy)-::US11203571, Compound 90

SMILES COc1ccc(Oc2cc(cc(c2C(=O)Nc2cccc(c2)S(N)(=O)=O)C(F)(F)F)C(F)(F)F)cc1F

InChI Key InChIKey=KAYRZLWFCJSCJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529538   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529538(US11203571, Compound 90 | 2-(3-fluoro-4-methoxyphe...)
Affinity DataIC50: 7nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent