BDBM529379 US11198699, Compound 9

SMILES Nc1nc2cc(OC[C@@]3(F)C[C@H]([C@H](O)[C@@H]3O)n3ccc4c(N)ncnc34)ccc2cc1Br

InChI Key InChIKey=GUIQOTFUZWXBTM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 529379   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aligos Therapeutics

US Patent
LigandPNGBDBM529379(US11198699, Compound 9)
Affinity DataIC50: 1nMAssay Description:Assay 2: Compounds were tested for inhibition of methyltransferase activity in 384-well plate assay format using mass spectrometry technology. In thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aligos Therapeutics

US Patent
LigandPNGBDBM529379(US11198699, Compound 9)
Affinity DataIC50: 1nMAssay Description:Assay 1: Compounds were tested for inhibition of methyltransferase activity in a radioisotope filter binding assay, similar to previously described i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
US Patent