BDBM529372 US11198699, Compound 2

SMILES CC[C@]1(CCc2ccc3ccc(N)nc3n2)C[C@H]([C@@H]2OC(C)(C)O[C@H]12)n1ccc2c(N)ncnc12

InChI Key InChIKey=RSZYMIYAQBVTGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 529372   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aligos Therapeutics

US Patent
LigandPNGBDBM529372(US11198699, Compound 2)
Affinity DataIC50: 1nMAssay Description:Assay 2: Compounds were tested for inhibition of methyltransferase activity in 384-well plate assay format using mass spectrometry technology. In thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aligos Therapeutics

US Patent
LigandPNGBDBM529372(US11198699, Compound 2)
Affinity DataIC50: 1nMAssay Description:Assay 1: Compounds were tested for inhibition of methyltransferase activity in a radioisotope filter binding assay, similar to previously described i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
US Patent