BDBM528979 US11198695, Example I-190::US11198695, Example II-143::US20240374587, Example I-190

SMILES CS(=O)(=O)CC(=O)Nc1c2c(C[C@]3(CCc4cc(OCC(F)(F)F)ccc34)NC2=O)nn1-c1ccc(cn1)C#N

InChI Key InChIKey=BXFPSVMWPYTPNT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 528979   

LigandPNGBDBM528979(US11198695, Example II-143 | US11198695, Example I...)
Affinity DataIC50: 2.90nMAssay Description:Solutions of the compounds of the present invention in DMSO were each aliquoted into 0.2-μL portions in a 384-well polystyrene microplate produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
Go to US Patent

LigandPNGBDBM528979(US11198695, Example II-143 | US11198695, Example I...)
Affinity DataIC50: 0.706nMAssay Description:Solutions of the compounds of the present invention in DMSO were each aliquoted into 0.2-μL portions in a 384-well polystyrene microplate produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2022
Entry Details
Go to US Patent

LigandPNGBDBM528979(US11198695, Example II-143 | US11198695, Example I...)
Affinity DataIC50: 2.90nMAssay Description:Solutions of the compounds of the present invention in DMSO were each aliquoted into 0.2·μL portions in a 384-well polystyrene microplate produced by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent