BDBM528647 US11192900, Compound 661::US11192900, Example S-71

SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-n1cc(Cl)c(=O)c2ccccc12

InChI Key InChIKey=MEURNDMYSIQSGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 528647   

TargetBromodomain-containing protein 4 [58-164](Human)
Nuvation Bio

US Patent
LigandPNGBDBM528647(US11192900, Compound 661 | US11192900, Example S-7...)
Affinity DataIC50: 20nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandPNGBDBM528647(US11192900, Compound 661 | US11192900, Example S-7...)
Affinity DataIC50: 5nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent