BDBM528637 US11192900, Compound 583::US11192900, Example S-61

SMILES Cn1cc(-c2cc(NC(=O)C=C)ccc2Oc2c(F)cccc2F)c2ccccc2c1=O

InChI Key InChIKey=CEFWZKIKWHGUBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 528637   

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandPNGBDBM528637(US11192900, Compound 583 | US11192900, Example S-6...)
Affinity DataIC50: 78nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent