BDBM528466 US11191762, Example 161.0

SMILES COc1cccc(OC)c1-n1c(COC(C)C)nnc1NS(=O)(=O)[C@@H](C)[C@H](C)c1ncc(Cl)cn1

InChI Key InChIKey=UMHYREBSKZSMGF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 528466   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM528466(US11191762, Example 161.0)
Affinity DataEC50:  2.20nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent