BDBM528441 US11191762, Example 131.0

SMILES COCc1nnc(NS(=O)(=O)[C@H](OC)[C@@H](C)c2ncc(Cl)cn2)n1-c1c(F)cccc1F

InChI Key InChIKey=CRERNSMQSRDWNK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 528441   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM528441(US11191762, Example 131.0)
Affinity DataEC50:  20nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent