BDBM528027 US11180482, Example I-9

SMILES COc1c(Nc2ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n2)cc2CN3CCCCC3Cc2c1N

InChI Key InChIKey=MHWKZCRFUVAIPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 528027   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Ariad Pharmaceuticals

US Patent
LigandPNGBDBM528027(US11180482, Example I-9)
Affinity DataIC50: 55nMAssay Description:The enzymatic activity of Wild Type HPK1 (MAP4K1) Kinase was measured in the presence or absence of an inhibitor compound of the present disclosure b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent