BDBM526935 (S)-1-(3-(8-amino-1-(4-phenoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-3-yl)piperidin-1-yl)prop-2-en-1-one (Compound 38)::US11186578, Example 7

SMILES Nc1nccn2c(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=VHHPPFUJDVUTDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526935   

TargetTyrosine-protein kinase BTK(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM526935((S)-1-(3-(8-amino-1-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 1nMAssay Description:BTK (Invitrogen, catalog number: PR5442A), HTRF-TK kit (Cisbio, catalog number: 62TK0PEC), MgCl2 (SIGMA, catalog number: 63020-1L), ATP (Sigma, catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
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