BDBM526875 US11186577, Cmpd. No. 223

SMILES Fc1ccc(nc1)N1CC2(CC(C2)c2nnc3CN(Cc4cc(Cl)ccc4-n23)C2CC2)C1

InChI Key InChIKey=KYVUCPRQLQJUBV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 526875   

TargetVasopressin V2 receptor(Human)
Blackthorn Therapeutics

US Patent
LigandPNGBDBM526875(US11186577, Cmpd. No. 223)
Affinity DataIC50: 100nMAssay Description:The purpose of the assay was to determine the inhibitory effect of synthesized compounds on the Vasopressin receptor 2. The assay was performed in co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Blackthorn Therapeutics

US Patent
LigandPNGBDBM526875(US11186577, Cmpd. No. 223)
Affinity DataIC50: 100nMAssay Description:The purpose of this assay was to determine the inhibitory effect of synthesized compounds on the Vasopressin V1a receptor. The assay as performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetOxytocin receptor(Human)
Blackthorn Therapeutics

US Patent
LigandPNGBDBM526875(US11186577, Cmpd. No. 223)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay was performed in CHEM-1 cells expressing the human Oxytocin Receptor (hOTR) to determine the inhibitory effect of the compounds of the inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent