BDBM526317 US11186544, Example 213

SMILES CS(=O)(=O)Nc1ccccc1-c1ccc(cc1)N1C[C@H](O)C[C@@H](NC(=O)Nc2ccc(cc2)C(F)(F)F)C1=O

InChI Key InChIKey=SMZKQGOYGYIKNM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 526317   

TargetN-formyl peptide receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM526317(US11186544, Example 213)
Affinity DataEC50:  0.75nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

TargetfMet-Leu-Phe receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM526317(US11186544, Example 213)
Affinity DataEC50:  110nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent