BDBM526078 US11185537, Compound I-8::US11185537, Compound I-9::trans-3-(5-(methyl(-2- (methylamino)cyclohexyl)amino)-1- oxoisoindolin-2-yl)piperidine-2,6-dione.

SMILES CN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O

InChI Key InChIKey=PRGCLFLBCUVASG-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 526078   

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50:  113nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetDNA-binding protein Ikaros(Human)
Novartis

US Patent
LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50:  103nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

TargetDNA-binding protein Ikaros(Human)
Novartis

US Patent
LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent

LigandPNGBDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
Go to US Patent