BDBM526019 (S)-2-fluoro-5-methyl-4-((1-phenylpropyl)thio)-N-(thiazol-2-yl)benzenesulfonamide::US11174268, Example 126

SMILES CC[C@H](Sc1cc(F)c(cc1C)S(=O)(=O)Nc1nccs1)c1ccccc1

InChI Key InChIKey=BKBBARITZRESJB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 526019   

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM526019((S)-2-fluoro-5-methyl-4-((1-phenylpropyl)thio)-N-(...)
Affinity DataIC50: 114nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM526019((S)-2-fluoro-5-methyl-4-((1-phenylpropyl)thio)-N-(...)
Affinity DataIC50: 1.14E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM526019((S)-2-fluoro-5-methyl-4-((1-phenylpropyl)thio)-N-(...)
Affinity DataIC50: 147nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent