BDBM525865 5-(6,6-dimethyl-5-oxo-1,2,3,7,8,9-hexahydropyrazolo[1,2-a]diazepin-3-yl)pyridine-3-carbonitrile::US11174262, Example 9

SMILES CC1(C)CCCN2CCC(N2C1=O)c1cncc(c1)C#N

InChI Key InChIKey=LAODNOQGDMJAOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525865   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Denali Therapeutics

US Patent
LigandPNGBDBM525865(5-(6,6-dimethyl-5-oxo-1,2,3,7,8,9-hexahydropyrazol...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent