BDBM525386 US11174232, Compound 63

SMILES CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1cnc(NC(=O)\C=C\CN2CCOCC2)c(F)c1

InChI Key InChIKey=CUBDFKPNPMKIJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525386   

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM525386(US11174232, Compound 63)
Affinity DataIC50: 62.5nMAssay Description:The ability of compounds to inhibit CDK7 kinase activity was tested in a TR-FRET assay using 5 nM of CDK7/CycH/MNAT1 obtained from Invitrogen, USA. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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