BDBM525279 US11173137, Compound FA26::US11173137, Compound AK3-98B

SMILES Cc1ccc(Cl)c2[nH]c3c(ccc(F)c3c12)C([O-])=O

InChI Key InChIKey=HPPILTSFNNPAGH-UHFFFAOYSA-M

Data  11 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 525279   

TargetChloride channel protein 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataIC50: 6.90E+4nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetChloride channel protein 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataIC50: 200nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetChloride intracellular channel protein 1(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataIC50: 3.00E+7nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetAlpha-2A adrenergic receptor(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi:  3.00E+3nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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Target5-hydroxytryptamine receptor 1A(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M5(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 1(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 4(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 5(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 6(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 8(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525279(US11173137, Compound FA26 | US11173137, Compound ...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent