BDBM525172 Benzyl N [(1S) 1 [[(2 chloroacetyl) (1H pyrazol 3 ylmethyl)amino]carbamoyl] 3 methyl butyl]carbamate::WO2022043374, Example 23

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NN(Cc1cc[nH]n1)C(=O)CCl

InChI Key InChIKey=QEVGXZNIRSQQAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525172   

TargetReplicase polyprotein 1ab(2019-nCoV)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM525172(WO2022043374, Example 23 | Benzyl N [(1S) 1 [[(2 c...)
Affinity DataIC50: 34nMAssay Description:For the SARS-CoV-2 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV-2 3CL protease were mixed with serial dilutions of each c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
WIPO WO2022043374

TargetReplicase polyprotein 1ab(2019-nCoV)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM525172(WO2022043374, Example 23 | Benzyl N [(1S) 1 [[(2 c...)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLpro expressed in Escherichia coli BL21 DE3 using FAM-KTSAVLQSGFRKMEK-TAMRA fluorogenic peptide as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed