BDBM525154 Benzyl N-[(1S)-1-[[(3-amino-3-oxo-propyl)-(2-chloroacetyl)amino]carbamoyl]-3-methyl-butyl]carbamate::WO2022043374, Example 2

SMILES CC(C)C[C@@H](C(=O)NN(CCC(=O)N)C(=O)CCl)NC(=O)OCc1ccccc1

InChI Key InChIKey=SEDQMDCLDZNPIX-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525154   

TargetReplicase polyprotein 1ab(2019-nCoV)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM525154(WO2022043374, Example 2 | Benzyl N-[(1S)-1-[[(3-am...)
Affinity DataIC50: 17nMAssay Description:For the SARS-CoV-2 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV-2 3CL protease were mixed with serial dilutions of each c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
WIPO WO2022043374

TargetReplicase polyprotein 1ab(2019-nCoV)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM525154(WO2022043374, Example 2 | Benzyl N-[(1S)-1-[[(3-am...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLpro expressed in Escherichia coli BL21 DE3 using FAM-KTSAVLQSGFRKMEK-TAMRA fluorogenic peptide as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed