BDBM524542 US11168089, Ex. No. 18::US11873304, Example 18

SMILES CCN(Cc1cccc(F)c1C(O)c1nc2cc(nc(N)n2n1)-c1cccc(C#N)c1F)[C@H]1CCNC1=O

InChI Key InChIKey=YLLJNDJPLNIZPD-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 524542   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandPNGBDBM524542(US11168089, Ex. No. 18 | US11873304, Example 18)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM524542(US11168089, Ex. No. 18 | US11873304, Example 18)
Affinity DataKi: <10nMAssay Description:Assays were conducted in black low volume 384-well polystyrene plates (Greiner 784076-25) in a final volume of 10 μL. Test compounds were first ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM524542(US11168089, Ex. No. 18 | US11873304, Example 18)
Affinity DataKi: <10nMAssay Description:Assays were conducted in black low volume 384-well polystyrene plates (Greiner 784076-25) in a final volume of 10 μL. Test compounds were first ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent