BDBM524487 Preparation of 1-isopropyl-N-(5-(piperazin-1-yl)pyridin-2-yl)-4,5-dihydro-1H-pyrazolo[4,3H]quinazolin-8-amine ::US11168088, Compound P-25

SMILES CC(C)n1ncc2CCc3cnc(Nc4ccc(cn4)N4CCNCC4)nc3-c12

InChI Key InChIKey=OKMDOAKJTIGKOT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524487   

LigandPNGBDBM524487(US11168088, Compound P-25 | Preparation of 1-isopr...)
Affinity DataIC50: 9nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524487(US11168088, Compound P-25 | Preparation of 1-isopr...)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524487(US11168088, Compound P-25 | Preparation of 1-isopr...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524487(US11168088, Compound P-25 | Preparation of 1-isopr...)
Affinity DataIC50: 8.52E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent