BDBM524479 Preparation of 9-isopropyl-8-methyl-N-(5-(piperazin-1-yl)pyridin-2-yl)-6,8-dihydro-5H-pyrazolo[3,4-H]quinazolin-2-amine ::US11168088, Compound P-14

SMILES CC(C)c1c2C3N=C(Cc4ccc(cn4)N4CCNCC4)N=CC3CCc2nn1C

InChI Key InChIKey=AKCCJVSVJFBBOF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524479   

LigandPNGBDBM524479(US11168088, Compound P-14 | Preparation of 9-isopr...)
Affinity DataIC50: 5nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

LigandPNGBDBM524479(US11168088, Compound P-14 | Preparation of 9-isopr...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

LigandPNGBDBM524479(US11168088, Compound P-14 | Preparation of 9-isopr...)
Affinity DataIC50: 1.02E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524479(US11168088, Compound P-14 | Preparation of 9-isopr...)
Affinity DataIC50: 523nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent