BDBM524463 2-((2S,4R)-4-amino-1-(4- chlorobenzo[b]thiophene-2- carbonyl)pyrrolidin-2-yl)-N-((S)-6- guanidino-1-(methylamino)-1- oxohexan-2-yl)thiazole-4-carboxamide::US11168083, Example 63

SMILES CNC(=O)[C@H](CCCCNC(N)=N)NC(=O)c1csc(n1)[C@@H]1C[C@@H](N)CN1C(=O)c1cc2c(Cl)cccc2s1

InChI Key InChIKey=SNRDAMCHFNCWJG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524463   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM524463(2-((2S,4R)-4-amino-1-(4- chlorobenzo[b]thiophene-2...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2022
Entry Details
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