BDBM524455 2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyridine-2- carbonyl)pynolidin-2-yl)-N-(4- (aminomethyl)phenethyl)thiazole-4- carboxamide::US11168083, Example 54

SMILES NCc1ccc(CCNC(=O)c2csc(n2)[C@@H]2C[C@@H](N)CN2C(=O)c2cn3cc(Cl)ccc3n2)cc1

InChI Key InChIKey=YUPDPXYEIFAQRA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524455   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM524455(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  3.00E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent