BDBM524451 2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyridine-2- carbonyl)pyrrolidin-2-yl)-N-(4- (aminomethyl)benzyl)thiazole-4- carboxamide::US11168083, Example 50

SMILES NCc1ccc(CNC(=O)c2csc(n2)[C@@H]2C[C@@H](N)CN2C(=O)c2cn3cc(Cl)ccc3n2)cc1

InChI Key InChIKey=FHGGDJNWGJXNMM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524451   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM524451(2-((2S,4R)-4-amino-1-(6- chloroimidazo[1,2-a]pyrid...)
Affinity DataEC50:  7.50E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2022
Entry Details
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