BDBM524443 2-((2S,4R)-4-amino-1-(6- chloroquinoline-2-carbonyl)pyrrolidin- 2-yl)-N-((S)-6-guanidino-1- (methylamino)-1-oxohexan-2- yl)thiazole-4-carboxamide::US11168083, Example 42

SMILES CNC(=O)[C@H](CCCCNC(N)=N)NC(=O)c1csc(n1)[C@@H]1C[C@@H](N)CN1C(=O)c1ccc2cc(Cl)ccc2n1

InChI Key InChIKey=GEJBSTPNTAGZPN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524443   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM524443(2-((2S,4R)-4-amino-1-(6- chloroquinoline-2-carbony...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2022
Entry Details
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