BDBM524406 2-((R)-1-(6-Chloroimidazo[1,2-a]pyridine-2-carbonyl)pyrrolidin-2-yl)-N ((S)-6-guanidino-1-(methylamino)-1-oxohexan-2-yl)thiazole-4-carboxamide::US11168083, Example 3

SMILES CNC(=O)[C@H](CCCCNC(N)=N)NC(=O)c1csc(n1)[C@H]1CCCN1C(=O)c1cn2cc(Cl)ccc2n1

InChI Key InChIKey=JYHRVUUCZYFFGN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524406   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM524406(2-((R)-1-(6-Chloroimidazo[1,2-a]pyridine-2-carbony...)
Affinity DataEC50: >9.90E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2022
Entry Details
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