BDBM524399 4-(5-(4-methyl-3,4-dihydro-2H- benzo[b][1,4]oxazin-7-yl)-1-(piperidin-4- ylmethyl)-1H-pyrrolo[2,3-c]pyridin-4- yl)benzonitrile::US11168082, Cpd. No. 98

SMILES CN1CCOc2cc(ccc12)-c1ncc2n(CC3CCNCC3)ccc2c1-c1ccc(cc1)C#N

InChI Key InChIKey=RSIWUODOHJGCRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524399   

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524399(US11168082, Cpd. No. 98 | 4-(5-(4-methyl-3,4-dihyd...)
Affinity DataIC50: 4.10nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524399(US11168082, Cpd. No. 98 | 4-(5-(4-methyl-3,4-dihyd...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed