BDBM524394 3-methyl-4-(5-(1-methyl-1H-indazol-5- yl)-1-(piperidin-4-ylmethyl)-1H- pyrrolo[2,3-c]pyridin-4-yl)benzonitrile::US11168082, Cpd. No. 93

SMILES Cc1cc(ccc1-c1c(ncc2n(CC3CCNCC3)ccc12)-c1ccc2n(C)ncc2c1)C#N

InChI Key InChIKey=KIUWPJWRKRNSIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524394   

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524394(US11168082, Cpd. No. 93 | 3-methyl-4-(5-(1-methyl-...)
Affinity DataIC50: 314nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524394(US11168082, Cpd. No. 93 | 3-methyl-4-(5-(1-methyl-...)
Affinity DataIC50: 215nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed