BDBM524390 3-fluoro-4-(5-(1-methyl-1H-indazol-5-yl)- 1-(piperidin-4-ylmethyl)-1H-pyrrolo[2,3- c]pyridin-4-yl)benzonitrile::US11168082, Cpd. No. 89

SMILES Cn1ncc2cc(ccc12)-c1ncc2n(CC3CCNCC3)ccc2c1-c1ccc(cc1F)C#N

InChI Key InChIKey=VCIGAEJLDFJCIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524390   

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524390(US11168082, Cpd. No. 89 | 3-fluoro-4-(5-(1-methyl-...)
Affinity DataIC50: 38.1nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524390(US11168082, Cpd. No. 89 | 3-fluoro-4-(5-(1-methyl-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed