BDBM524376 4-(5-(1-methyl-1H-indazol-5-yl)-1-(3- (methylamino)propyl)-1H-pyrrolo[2,3- c]pyridin-4-yl)benzonitrile::US11168082, Cpd. No. 74

SMILES CNCCCn1ccc2c(-c3ccc(cc3)C#N)c(ncc12)-c1ccc2n(C)ncc2c1

InChI Key InChIKey=SMRORBCILSOJLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524376   

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524376(US11168082, Cpd. No. 74 | 4-(5-(1-methyl-1H-indazo...)
Affinity DataIC50: 39.4nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524376(US11168082, Cpd. No. 74 | 4-(5-(1-methyl-1H-indazo...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed