BDBM524375 4-(1-(4-aminobutyl)-5-(1-methyl-1H- indazol-5-yl)-1H-pyrrolo[2,3-c]pyridin-4- yl)benzonitrile::US11168082, Cpd. No. 73

SMILES Cn1ncc2cc(ccc12)-c1ncc2n(CCCCN)ccc2c1-c1ccc(cc1)C#N

InChI Key InChIKey=SZEIPAHADBWABM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524375   

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524375(US11168082, Cpd. No. 73 | 4-(1-(4-aminobutyl)-5-(1...)
Affinity DataIC50: 13nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524375(US11168082, Cpd. No. 73 | 4-(1-(4-aminobutyl)-5-(1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed