BDBM524351 2-fluoro-4-(5-(1-melhyl-1H-indazol-5-yl)- 1-(pyridin-3-ylmethyl)-1H-pyrrolo[2,3- c]pyridin-4-yl)benzonitrile::US11168082, Cpd. No. 47

SMILES Cn1ncc2cc(ccc12)-c1ncc2n(Cc3cccnc3)ccc2c1-c1ccc(C#N)c(F)c1

InChI Key InChIKey=BNODWXYYLLHHLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524351   

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524351(US11168082, Cpd. No. 47 | 2-fluoro-4-(5-(1-melhyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524351(US11168082, Cpd. No. 47 | 2-fluoro-4-(5-(1-melhyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed