BDBM524313 (R)-4-(1-(pyrrolidin-3-ylmethyl)-5-(p- tolyl)-1H-pyrrolo[2,3-c]pyridin-4- yl)benzonitrile::US11168082, Cpd. No. 9

SMILES Cc1ccc(cc1)-c1ncc2n(C[C@@H]3CCNC3)ccc2c1-c1ccc(cc1)C#N

InChI Key InChIKey=XOVXJEMBJYKPFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524313   

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524313(US11168082, Cpd. No. 9 | (R)-4-(1-(pyrrolidin-3-yl...)
Affinity DataIC50: 130nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM524313(US11168082, Cpd. No. 9 | (R)-4-(1-(pyrrolidin-3-yl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed