BDBM524218 US11168075, Compound Formula (IIe)

SMILES CSc1nc(O)c(C(=O)Nc2ccc(cc2)-c2cnn[nH]2)c(=O)[nH]1

InChI Key InChIKey=GXZDQJWPRRTCOO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 524218   

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM524218(US11168075, Compound Formula (IIe))
Affinity DataIC50: 25nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM524218(US11168075, Compound Formula (IIe))
Affinity DataIC50: 50nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM524218(US11168075, Compound Formula (IIe))
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of XO (unknown origin) assessed as decrease in uric acid levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed