BDBM524066 1-({3-[2-(4-Chlorophenyl)-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl}methyl)-7-methyl-1,7-dihydro-6H-purin-6-one::US11136336, WO2017/060488 Example 53

SMILES Cn1cnc2ncn(Cc3nc(CC(O)c4ccc(Cl)cc4)no3)c(=O)c12

InChI Key InChIKey=FELFYFLOCBXASZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524066   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524066(US11136336, WO2017/060488 Example 53 | 1-({3-[2-(4...)
Affinity DataIC50: 36nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent