BDBM524045 US11136333, Compound 12d

SMILES Clc1cccc(Cl)c1-c1cc2cnc(Nc3cccc(c3)[N+]#[C-])nc2oc1=O

InChI Key InChIKey=FAFOTNJCIQRUCI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524045   

TargetTyrosine-protein kinase ABL1(Human)
Texas A&M University System

US Patent
LigandPNGBDBM524045(US11136333, Compound 12d)
Affinity DataKd:  2.60nMAssay Description:This assay is described in https://www.discoverx.com/kinase-data-sheets/abl1-nonphosphorylated.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetTyrosine-protein kinase ABL1(Human)
Texas A&M University System

US Patent
LigandPNGBDBM524045(US11136333, Compound 12d)
Affinity DataIC50: 42.6nMAssay Description:IC50 against Abelson kinase ABL1 was determined by Life Technologies corporation though the Z′-LITE biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent