BDBM523848 US11136320, Compound 69

SMILES COc1nc2N(CCCc2cc1CN1CCN(C)CC1=O)C(=O)Nc1cc(N[C@H](C)CS(C)=O)c(cn1)C#N

InChI Key InChIKey=QXVCTKMARCABBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523848   

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM523848(US11136320, Compound 69)
Affinity DataIC50: 2.10nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent