BDBM523843 N-(5-cyano-4-((tetrahydrothiophene-3-yl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1 (2H)-carboxamide::US11136320, Compound 5

SMILES COc1nc2N(CCCc2cc1CN1CCN(C)CC1=O)C(=O)Nc1cc(NC2CCSC2)c(cn1)C#N

InChI Key InChIKey=FSQQEOYNTFNNJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523843   

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM523843(US11136320, Compound 5 | N-(5-cyano-4-((tetrahydro...)
Affinity DataIC50: 2nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2022
Entry Details
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