BDBM523778 US11136312, Compound AH-1-86

SMILES C(Cc1c[nH]cn1)Cn1c(SCc2ccccc2)nnc1C1=CNC2C=CC=CC12

InChI Key InChIKey=KOHHPNPAOWZSBW-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 523778   

TargetSomatostatin receptor type 3(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523778(US11136312, Compound AH-1-86)
Affinity DataEC50:  105nMAssay Description:Measurement of forskolin stimulated inhibition of cAMP was performed via time-resolved fluorescence resonance energy transfer (TR-FRET) LANCE assay (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetSomatostatin receptor type 4(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523778(US11136312, Compound AH-1-86)
Affinity DataKi:  76.1nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetSomatostatin receptor type 1(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523778(US11136312, Compound AH-1-86)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetSomatostatin receptor type 2(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523778(US11136312, Compound AH-1-86)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetSomatostatin receptor type 3(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523778(US11136312, Compound AH-1-86)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetSomatostatin receptor type 5(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523778(US11136312, Compound AH-1-86)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent